A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines

Cardiac glycosides are well known in the treatment of cardiovascular diseases; however, their application as treatment option for cancer patients is under discussion. We showed that the cardiac glycoside digitoxin and its analog AMANTADIG can inhibit the growth of renal cell carcinoma (RCC) cell lin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Nolte, Elke, Wach, Sven, Silva, Izabella Thais, Lukat, Sabine, Ekici, Arif B., Munkert, Jennifer, Müller-Uri, Frieder, Kreis, Wolfgang, Simões, Cláudia Maria Oliveira, Vera, Julio, Wullich, Bernd, Taubert, Helge, Lai, Xin
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355295/
https://ncbi.nlm.nih.gov/pubmed/28099931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14644
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker