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MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering
The receptor tyrosine kinase MET and its ligand, the hepatocyte growth factor, are essential to embryonic development, whereas deregulation of MET signaling is associated with tumorigenesis leading to various cancers, including lung carcinoma. Mutations in the MET kinase domain lead to constitutive...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355264/ https://ncbi.nlm.nih.gov/pubmed/28061464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14499 |
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