MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering

The receptor tyrosine kinase MET and its ligand, the hepatocyte growth factor, are essential to embryonic development, whereas deregulation of MET signaling is associated with tumorigenesis leading to various cancers, including lung carcinoma. Mutations in the MET kinase domain lead to constitutive...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Montagne, Rémi, Baranzelli, Anne, Muharram, Ghaffar, Catherine, Leroy, Lesaffre, Marie, Vinchent, Audrey, Kherrouche, Zoulika, Werkmeister, Elisabeth, Cortot, Alexis B, Tulasne, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355264/
https://ncbi.nlm.nih.gov/pubmed/28061464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14499
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