Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

The Keap1/Nrf2 pathway is a master regulator of the cellular redox state through the induction of several antioxidant defence genes implicated in chemotherapeutic drugs resistance of tumor cells. An increasing body of evidence supports a key role for Keap1/Nrf2 pathway in kidney diseases and renal c...

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Pubblicato in:Oncotarget
Autori principali: Fabrizio, Federico Pio, Costantini, Manuela, Copetti, Massimiliano, la Torre, Annamaria, Sparaneo, Angelo, Fontana, Andrea, Poeta, Luana, Gallucci, Michele, Sentinelli, Steno, Graziano, Paolo, Parente, Paola, Pompeo, Vincenzo, Salvo, Laura De, Simone, Giuseppe, Papalia, Rocco, Picardo, Francesco, Balsamo, Teresa, Flammia, Gerardo Paolo, Trombetta, Domenico, Pantalone, Angela, Kok, Klaas, Paranita, Ferronika, Muscarella, Lucia Anna, Fazio, Vito Michele
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355256/
https://ncbi.nlm.nih.gov/pubmed/28061437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14492
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