Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma

The Keap1/Nrf2 pathway is a master regulator of the cellular redox state through the induction of several antioxidant defence genes implicated in chemotherapeutic drugs resistance of tumor cells. An increasing body of evidence supports a key role for Keap1/Nrf2 pathway in kidney diseases and renal c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fabrizio, Federico Pio, Costantini, Manuela, Copetti, Massimiliano, la Torre, Annamaria, Sparaneo, Angelo, Fontana, Andrea, Poeta, Luana, Gallucci, Michele, Sentinelli, Steno, Graziano, Paolo, Parente, Paola, Pompeo, Vincenzo, Salvo, Laura De, Simone, Giuseppe, Papalia, Rocco, Picardo, Francesco, Balsamo, Teresa, Flammia, Gerardo Paolo, Trombetta, Domenico, Pantalone, Angela, Kok, Klaas, Paranita, Ferronika, Muscarella, Lucia Anna, Fazio, Vito Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355256/
https://ncbi.nlm.nih.gov/pubmed/28061437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14492
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