Impact of NUDT15 polymorphisms on thiopurines-induced myelotoxicity and thiopurines tolerance dose

Thiopurines are widely used as anticancer and immunosuppressive agents. However, life-threatening myelotoxicity has been noticed and largely explained by genetic variations, including NUDT15 polymorphisms (e.g., rs116855232). In this study, we conduct a meta-analysis to investigate the impact of rs1...

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Udgivet i:Oncotarget
Main Authors: Yin, Dandan, Xia, Xuyang, Zhang, Junlong, Zhang, Shouyue, Liao, Fei, Zhang, Ge, Zhang, Yan, Hou, Qianqian, Yang, Xue, Wang, Hong, Ma, Zhigui, Wang, Heyao, Zhu, Yiping, Zhang, Wei, Wang, Yuelan, Liu, Bo, Wang, Lanlan, Xu, Heng, Shu, Yang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355121/
https://ncbi.nlm.nih.gov/pubmed/28088792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14594
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