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Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma

Hypoxia-inducible factors (HIFs) are key regulators in oxygen homeostasis. Their stabilization and activity are regulated by prolyl hydroxylase domain (PHD)-1, -2, -3 and factor inhibiting HIF (FIH). This study investigated the relation between these oxygen sensors and the clinical behaviors and pro...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Ma, Mingyang, Hua, Shuyao, Li, Gang, Wang, Sumei, Cheng, Xue, He, Songqing, Wu, Ping, Chen, Xiaoping
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355071/
https://ncbi.nlm.nih.gov/pubmed/28099905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14677
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