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The pre-existing population of 5S rRNA effects p53 stabilization during ribosome biogenesis inhibition

Pre-ribosomal complex RPL5/RPL11/5S rRNA (5S RNP) is considered the central MDM2 inhibitory complex that control p53 stabilization during ribosome biogenesis inhibition. Despite its role is well defined, the dynamic of 5S RNP assembly still requires further characterization. In the present work, we...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Onofrillo, Carmine, Galbiati, Alice, Montanaro, Lorenzo, Derenzini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354829/
https://ncbi.nlm.nih.gov/pubmed/28032591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13833
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