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Decline in arylsulfatase B leads to increased invasiveness of melanoma cells

Arylsulfatase B (ARSB; N-acetylgalactosamine 4-sulfatase) is reduced in several malignancies, but levels in melanoma have not been investigated previously. Experiments were performed in melanoma cell lines to determine ARSB activity and impact on melanoma invasiveness. ARSB activity was reduced ~50%...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Bhattacharyya, Sumit, Feferman, Leo, Terai, Kaoru, Dudek, Arkadiusz Z., Tobacman, Joanne K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354821/
https://ncbi.nlm.nih.gov/pubmed/27926479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13751
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