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Increased Expression of Colonic Wnt9A through Sp1-mediated Transcriptional Effects involving Arylsulfatase B, Chondroitin 4-Sulfate, and Galectin-3

In cultured human colonic epithelial cells and mouse colonic tissue, exposure to the common food additive carrageenan leads to inflammation, activation of Wnt signaling, increased Wnt9A expression, and decline in the activity of the enzyme arylsulfatase B (ARSB; N-acetylgalactosamine-4-sulfatase). I...

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Autors principals: Bhattacharyya, Sumit, Feferman, Leo, Tobacman, Joanne K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067192/
https://ncbi.nlm.nih.gov/pubmed/24778176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561589
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