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Targeted activation of AMPK by GSK621 ameliorates H(2)O(2)-induced damages in osteoblasts
GSK621 is a novel AMP-activated protein kinase (AMPK) activator. This study tested its potential cytoprotective effect in hydrogen peroxide (H(2)O(2))-treated osteoblasts. In cultured MC3T3-E1 osteoblastic cells and primary murine osteoblasts, GSK621 significantly attenuated H(2)O(2)-induced cell de...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354679/ https://ncbi.nlm.nih.gov/pubmed/28060740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14454 |
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