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Heat shock protein 90 and calcineurin pathway inhibitors enhance the efficacy of triazoles against Scedosporium prolificans via induction of apoptosis

Scedosporium prolificans is a pathogenic mold resistant to current antifungals, and infection results in high mortality. Simultaneous targeting of both ergosterol biosynthesis and heat shock protein 90 (Hsp90) or the calcineurin pathway in S. prolificans may be an important strategy for enhancing th...

詳細記述

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書誌詳細
出版年:Microb Cell
主要な著者: Shirazi, Fazal, Kontoyiannis, Dimitrios P.
フォーマット: Artigo
言語:Inglês
出版事項: Shared Science Publishers OG 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354560/
https://ncbi.nlm.nih.gov/pubmed/28357242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.06.150
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