Assessing Tn5 and Sleeping Beauty for transpositional transgenesis by cytoplasmic injection into bovine and ovine zygotes

Transgenic domestic animals represent an alternative to bioreactors for large-scale production of biopharmaceuticals and could also provide more accurate biomedical models than rodents. However, their generation remains inefficient. Recently, DNA transposons allowed improved transgenesis efficiencie...

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Udgivet i:PLoS One
Main Authors: Bevacqua, R. J., Fernandez-Martin, R., Canel, N. G., Gibbons, A., Texeira, D., Lange, F., Vans Landschoot, G., Savy, V., Briski, O., Hiriart, M. I., Grueso, E., Ivics, Z., Taboga, O., Kues, W. A., Ferraris, S., Salamone, D. F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354444/
https://ncbi.nlm.nih.gov/pubmed/28301581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174025
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