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One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle

Genetically modified cattle are important for developing new biomedical models and for an improved understanding of the pathophysiology of zoonotic diseases. However, genome editing and genetic engineering based on somatic cell nuclear transfer suffer from a low overall efficiency. Here, we establis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Garrels, Wiebke, Talluri, Thirumala R., Apfelbaum, Ronja, Carratalá, Yanet P., Bosch, Pablo, Pötzsch, Kerstin, Grueso, Esther, Ivics, Zoltán, Kues, Wilfried A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764937/
https://ncbi.nlm.nih.gov/pubmed/26905416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21953
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