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One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle

Genetically modified cattle are important for developing new biomedical models and for an improved understanding of the pathophysiology of zoonotic diseases. However, genome editing and genetic engineering based on somatic cell nuclear transfer suffer from a low overall efficiency. Here, we establis...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Garrels, Wiebke, Talluri, Thirumala R., Apfelbaum, Ronja, Carratalá, Yanet P., Bosch, Pablo, Pötzsch, Kerstin, Grueso, Esther, Ivics, Zoltán, Kues, Wilfried A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764937/
https://ncbi.nlm.nih.gov/pubmed/26905416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21953
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