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The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia

Chronic myeloid leukemia (CML) treatment has been improved by tyrosine kinase inhibitors (TKIs) such as imatinib mesylate (IM) but various factors can cause TKI resistance in patients with CML. One factor which contributes to TKI resistance is a germline intronic deletion polymorphism in the BCL2-li...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Rauzan, Muhammad, Chuah, Charles T. H., Ko, Tun Kiat, Ong, S. Tiong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354438/
https://ncbi.nlm.nih.gov/pubmed/28301600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174107
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