The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia

Both germline polymorphisms and tumor-specific genetic alterations can determine the response of a cancer to a given therapy. We previously reported a germline deletion polymorphism in the BIM gene that was sufficient to mediate intrinsic resistance to tyrosine kinase inhibitors (TKI) in chronic mye...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ko, Tun Kiat, Chin, Hui San, Chuah, Charles T.H., Huang, John W.J., Ng, King-Pan, Khaw, Seong Lin, Huang, David C.S., Ong, S. Tiong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823067/
https://ncbi.nlm.nih.gov/pubmed/26517680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.5436
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados