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A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint
BRCA1-associated breast cancer exhibits significantly higher levels of chromosomal abnormalities than sporadic breast cancers. However, the molecular mechanisms regarding the roles of BRCA1 in maintaining genome integrity remain elusive. By using a mouse model deficient for Brca1 full-length isoform...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC535394/ https://ncbi.nlm.nih.gov/pubmed/15563594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407585101 |
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