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Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint

The spindle checkpoint ensures the accuracy of chromosome segregation during mitosis. The protein serine/threonine kinase, Mps1, is a critical component of the spindle checkpoint in human cells and regulates the kinetochore localization of key checkpoint proteins. The kinase activity of Mps1 is requ...

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Detalhes bibliográficos
Main Authors: Kang, Jungseog, Chen, Yue, Zhao, Yingming, Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154414/
https://ncbi.nlm.nih.gov/pubmed/18083840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710519105
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