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slo K(+) channel gene regulation mediates rapid drug tolerance

Changes in neural activity caused by exposure to drugs may trigger homeostatic mechanisms that attempt to restore normal neural excitability. In Drosophila, a single sedation with the anesthetic benzyl alcohol changes the expression of the slo K(+) channel gene and induces rapid drug tolerance. We d...

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Détails bibliographiques
Auteurs principaux: Ghezzi, Alfredo, Al-Hasan, Yazan M., Larios, Leo E., Bohm, Rudolf A., Atkinson, Nigel S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC535374/
https://ncbi.nlm.nih.gov/pubmed/15569939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405584101
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