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CREB regulation of BK channel gene expression underlies rapid drug tolerance

Pharmacodynamic tolerance is believed to involve homeostatic mechanisms initiated to restore normal neural function. Drosophila exposed to a sedating dose of an organic solvent, such as benzyl alcohol or ethanol, acquire tolerance to subsequent sedation by that solvent. The slo gene encodes BK type...

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Detalhes bibliográficos
Main Authors: Wang, Yan, Ghezzi, Alfredo, Yin, Jerry C.P., Atkinson, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796570/
https://ncbi.nlm.nih.gov/pubmed/19243452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2009.00479.x
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