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BK channels play a counter-adaptive role in drug tolerance and dependence
Disturbance of neural activity by sedative drugs has been proposed to trigger a homeostatic response that resists unfavorable changes in net cellular excitability, leading to tolerance and dependence. The Drosophila slo gene encodes a BK-type Ca(2+)-activated K(+) channel implicated in functional to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941274/ https://ncbi.nlm.nih.gov/pubmed/20798347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005439107 |
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