Structural basis of homo- and heterotrimerization of collagen I

Fibrillar collagen molecules are synthesized as precursors, procollagens, with large propeptide extensions. While a homotrimeric form (three α1 chains) has been reported in embryonic tissues as well as in diseases (cancer, fibrosis, genetic disorders), collagen type I usually occurs as a heterotrime...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Sharma, Urvashi, Carrique, Loïc, Vadon-Le Goff, Sandrine, Mariano, Natacha, Georges, Rainier-Numa, Delolme, Frederic, Koivunen, Peppi, Myllyharju, Johanna, Moali, Catherine, Aghajari, Nushin, Hulmes, David J. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353611/
https://ncbi.nlm.nih.gov/pubmed/28281531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14671
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