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Structural basis of homo- and heterotrimerization of collagen I
Fibrillar collagen molecules are synthesized as precursors, procollagens, with large propeptide extensions. While a homotrimeric form (three α1 chains) has been reported in embryonic tissues as well as in diseases (cancer, fibrosis, genetic disorders), collagen type I usually occurs as a heterotrime...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5353611/ https://ncbi.nlm.nih.gov/pubmed/28281531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14671 |
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