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On the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes

The canonical CysXXXCysXXCys motif is the hallmark of the Radical-SAM superfamily. This motif is responsible for the ligation of a [4Fe-4S] cluster containing a free coordination site available for SAM binding. The five enzymes MoaA, TYW1, MiaB, RimO and LipA contain in addition a second [4Fe-4S] cl...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Mulliez, Etienne, Duarte, Victor, Arragain, Simon, Fontecave, Marc, Atta, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352715/
https://ncbi.nlm.nih.gov/pubmed/28361051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00017
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