On the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes

The canonical CysXXXCysXXCys motif is the hallmark of the Radical-SAM superfamily. This motif is responsible for the ligation of a [4Fe-4S] cluster containing a free coordination site available for SAM binding. The five enzymes MoaA, TYW1, MiaB, RimO and LipA contain in addition a second [4Fe-4S] cl...

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Publicado en:Front Chem
Autores principales: Mulliez, Etienne, Duarte, Victor, Arragain, Simon, Fontecave, Marc, Atta, Mohamed
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352715/
https://ncbi.nlm.nih.gov/pubmed/28361051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2017.00017
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