Two Fe-S clusters catalyse sulfur insertion by Radical-SAM methylthiotransferases

How living organisms create carbon-sulfur bonds during biosynthesis of critical sulphur-containing compounds is still poorly understood. The methylthiotransferases MiaB and RimO catalyze sulfur insertion into tRNAs and ribosomal protein S12, respectively. Both belong to a sub-group of Radical-SAM en...

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Hoofdauteurs: Forouhar, Farhad, Arragain, Simon, Atta, Mohamed, Gambarelli, Serge, Mouesca, Jean-Marie, Hussain, Munif, Xiao, Rong, Kieffer-Jaquinod, Sylvie, Seetharaman, Jayaraman, Acton, Thomas B., Montelione, Gaetano T., Mulliez, Etienne, Hunt, John F., Fontecave, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118475/
https://ncbi.nlm.nih.gov/pubmed/23542644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1229
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