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Synthesis of Complex Tertiary Glycolates by Enantioconvergent Arylation of Stereochemically Labile α-Keto Esters

Enantioconvergent arylation reactions of boronic acids and racemic β-stereogenic α-keto esters have been developed. The reactions are catalyzed by a chiral (diene)Rh(I) complex and provide a wide array of β-stereogenic tertiary aryl glycolate derivatives with high levels of diastereo- and enantiosel...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Autores principales: Bartlett, Samuel L., Keiter, Kimberly M., Johnson, Jeffrey S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352479/
https://ncbi.nlm.nih.gov/pubmed/28252953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b00943
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