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Matrix rigidity regulates the microtubule network polarization in migration

The microtubule organizing center (MTOC) frequently polarizes to a position in front of the nucleus during cell migration, but recent work has shown conflicting evidence for the MTOC location in migratory polarized cells. Here, we show that subcellular localization of the MTOC is modulated by the ex...

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Detalles Bibliográficos
Publicado en:Cytoskeleton (Hoboken)
Main Authors: Raab, Matthew, Discher, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352467/
https://ncbi.nlm.nih.gov/pubmed/27935261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21349
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