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Persistence-driven durotaxis: Generic, directed motility in rigidity gradients

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a soft-to-stiff gradient. Using simple random walk models with control...

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Detalhes bibliográficos
Publicado no:Phys Rev Lett
Main Authors: Novikova, Elizaveta A., Raab, Matthew, Discher, Dennis E., Storm, Cornelis
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338469/
https://ncbi.nlm.nih.gov/pubmed/28256894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.118.078103
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