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Persistence-driven durotaxis: Generic, directed motility in rigidity gradients

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a soft-to-stiff gradient. Using simple random walk models with control...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Phys Rev Lett
Päätekijät: Novikova, Elizaveta A., Raab, Matthew, Discher, Dennis E., Storm, Cornelis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338469/
https://ncbi.nlm.nih.gov/pubmed/28256894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.118.078103
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