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Optimal matrix rigidity for stress fiber polarization in stem cells
The shape and differentiation of human mesenchymal stem cells is especially sensitive to the rigidity of their environment; the physical mechanisms involved are unknown. A theoretical model and experiments demonstrate here that the polarization/alignment of stress-fibers within stem cells is a non-m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885792/ https://ncbi.nlm.nih.gov/pubmed/20563235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nphys1613 |
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