Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

In immune cells, CD73 dephosphorylates and converts extracellular AMP into adenosine, which binds the A2A adenosine receptor (A2AR). Blockade of this interaction, which induces an immunosuppressed niche in the tumor microenvironment, represents a potential novel treatment strategy. The clinical sign...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Inoue, Yusuke, Yoshimura, Katsuhiro, Kurabe, Nobuya, Kahyo, Tomoaki, Kawase, Akikazu, Tanahashi, Masayuki, Ogawa, Hiroshi, Inui, Naoki, Funai, Kazuhito, Shinmura, Kazuya, Niwa, Hiroshi, Suda, Takafumi, Sugimura, Haruhiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352437/
https://ncbi.nlm.nih.gov/pubmed/28060732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14434
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