Prognostic impact of CD73 and A2A adenosine receptor expression in non-small-cell lung cancer

In immune cells, CD73 dephosphorylates and converts extracellular AMP into adenosine, which binds the A2A adenosine receptor (A2AR). Blockade of this interaction, which induces an immunosuppressed niche in the tumor microenvironment, represents a potential novel treatment strategy. The clinical sign...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Inoue, Yusuke, Yoshimura, Katsuhiro, Kurabe, Nobuya, Kahyo, Tomoaki, Kawase, Akikazu, Tanahashi, Masayuki, Ogawa, Hiroshi, Inui, Naoki, Funai, Kazuhito, Shinmura, Kazuya, Niwa, Hiroshi, Suda, Takafumi, Sugimura, Haruhiko
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352437/
https://ncbi.nlm.nih.gov/pubmed/28060732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14434
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