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The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKa/mTOR pathway in vitro and in vivo

Telmisartan, a widely used antihypertensive drug, is an angiotensin II type 1 (AT1) receptor blocker (ARB). This drug inhibits cancer cell proliferation, but the underlying mechanisms in various cancers, including esophageal cancer, remain unknown. The aim of the present study was to evaluate the ef...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Fujihara, Shintaro, Morishita, Asahiro, Ogawa, Kana, Tadokoro, Tomoko, Chiyo, Taiga, Kato, Kiyohito, Kobara, Hideki, Mori, Hirohito, Iwama, Hisakazu, Masaki, Tsutomu
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352420/
https://ncbi.nlm.nih.gov/pubmed/28052030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14345
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