The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKa/mTOR pathway in vitro and in vivo

Telmisartan, a widely used antihypertensive drug, is an angiotensin II type 1 (AT1) receptor blocker (ARB). This drug inhibits cancer cell proliferation, but the underlying mechanisms in various cancers, including esophageal cancer, remain unknown. The aim of the present study was to evaluate the ef...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fujihara, Shintaro, Morishita, Asahiro, Ogawa, Kana, Tadokoro, Tomoko, Chiyo, Taiga, Kato, Kiyohito, Kobara, Hideki, Mori, Hirohito, Iwama, Hisakazu, Masaki, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352420/
https://ncbi.nlm.nih.gov/pubmed/28052030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14345
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