Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model

Galectin-9 (Gal-9) enhances tumor immunity mediated by T cells, macrophages, and dendritic cells. Its expression level in various cancers correlates with prognosis. Furthermore, Gal-9 directly induces apoptosis in various cancers; however, its mechanism of action and bioactivity has not been clarifi...

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Udgivet i:Int J Mol Sci
Main Authors: Chiyo, Taiga, Fujita, Koji, Iwama, Hisakazu, Fujihara, Shintaro, Tadokoro, Tomoko, Ohura, Kyoko, Matsui, Takanori, Goda, Yasuhiro, Kobayashi, Nobuya, Nishiyama, Noriko, Yachida, Tatsuo, Morishita, Asahiro, Kobara, Hideki, Mori, Hirohito, Niki, Toshiro, Hirashima, Mitsuomi, Himoto, Takashi, Masaki, Tsutomu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600680/
https://ncbi.nlm.nih.gov/pubmed/31146370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112634
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