Nanometronomic treatment of 4T1 breast cancer with nanocaged doxorubicin prevents drug resistance and circumvents cardiotoxicity

Chemotherapeutic treatment of breast cancer is based on maximum tolerated dose (MTD) approach. However, advanced stage tumors are not effectively eradicated by MTD owing to suboptimal drug targeting, onset of therapeutic resistance and neoangiogenesis. In contrast, “metronomic” chemotherapy is based...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mazzucchelli, Serena, Bellini, Michela, Fiandra, Luisa, Truffi, Marta, Rizzuto, Maria A., Sorrentino, Luca, Longhi, Erika, Nebuloni, Manuela, Prosperi, Davide, Corsi, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352408/
https://ncbi.nlm.nih.gov/pubmed/28039473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14204
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