Heterogeneity and frequency of BRAF mutations in primary melanoma: Comparison between molecular methods and immunohistochemistry

Finding the best technique to identify BRAF mutations with a high sensitivity and specificity is mandatory for accurate patient selection for target therapy. BRAF mutation frequency ranges from 40 to 60% depending on melanoma clinical characteristics and detection technique used. Intertumoral hetero...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bruno, William, Martinuzzi, Claudia, Andreotti, Virginia, Pastorino, Lorenza, Spagnolo, Francesco, Dalmasso, Bruna, Cabiddu, Francesco, Gualco, Marina, Ballestrero, Alberto, Bianchi-Scarrà, Giovanna, Queirolo, Paola, Grillo, Federica, Mastracci, Luca, Ghiorzo, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352383/
https://ncbi.nlm.nih.gov/pubmed/28039443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14094
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