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BRAF-mutant melanoma: treatment approaches, resistance mechanisms, and diagnostic strategies
BRAF inhibitors vemurafenib and dabrafenib achieved improved overall survival over chemotherapy and have been approved for the treatment of BRAF-mutated metastatic melanoma. More recently, the combination of BRAF inhibitor dabrafenib with MEK inhibitor trametinib has shown improved progression-free...
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| Pubblicato in: | Onco Targets Ther |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303458/ https://ncbi.nlm.nih.gov/pubmed/25653539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S39096 |
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