α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagy

Macrophage apoptosis is salient in advanced atherosclerotic lesions and is induced by several stimuli including endoplasmic reticulum (ER) stress. This study examined that a-asarone present in purple perilla abrogated macrophage injury caused by oxysterols via ER stress- and autophagy-mediated mecha...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Park, Sin-Hye, Kang, Min-Kyung, Choi, Yean-Jung, Kim, Yun-Ho, Antika, Lucia Dwi, Kim, Dong Yeon, Lee, Eun-Jung, Lim, Soon Sung, Kang, Young-Hee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper: Pathology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352328/
https://ncbi.nlm.nih.gov/pubmed/28088783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14566
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