Chrysin ameliorates podocyte injury and slit diaphragm protein loss via inhibition of the PERK-eIF2α-ATF-CHOP pathway in diabetic mice

Glomerular epithelial podocytes are highly specialized cells that play a crucial role in maintaining normal function of the glomerular filtration barrier via their foot processes. Chrysin (5,7-dihydroxyflavone) is a natural flavonoid found in propolis and mushrooms that has anti-inflammatory, antiox...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Kang, Min-Kyung, Park, Sin-Hye, Kim, Yun-Ho, Lee, Eun-Jung, Antika, Lucia Dwi, Kim, Dong Yeon, Choi, Yean-Jung, Kang, Young-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547556/
https://ncbi.nlm.nih.gov/pubmed/28502979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.30
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