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Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice
During aging, uncontrolled epithelial cell proliferation in the uterus results in endometrial hyperplasia and/or cancer development. The mTOR signaling pathway is one of the major regulators of aging as suppression of this pathway prolongs lifespan in model organisms. Genetic alterations in this pat...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352319/ https://ncbi.nlm.nih.gov/pubmed/27980219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13919 |
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