Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice

During aging, uncontrolled epithelial cell proliferation in the uterus results in endometrial hyperplasia and/or cancer development. The mTOR signaling pathway is one of the major regulators of aging as suppression of this pathway prolongs lifespan in model organisms. Genetic alterations in this pat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Bajwa, Preety, Nielsen, Sarah, Lombard, Janine M., Rassam, Loui, Nahar, Pravin, Rueda, Bo R., Wilkinson, J. Erby, Miller, Richard A., Tanwar, Pradeep S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Priority Research Paper: Gerotarget
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352319/
https://ncbi.nlm.nih.gov/pubmed/27980219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13919
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg