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Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
Wnt/β-catenin signaling elicits context-dependent transcription switches that determine normal development and oncogenesis. These are mediated by the Wnt enhanceosome, a multiprotein complex binding to the Pygo chromatin reader and acting through TCF/LEF-responsive enhancers. Pygo renders this compl...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352222/ https://ncbi.nlm.nih.gov/pubmed/28296634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20882 |
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