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VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers
We have investigated the role of vascular-endothelial (VE)-cadherin in melanoma and breast cancer metastasis. We found that VE-cadherin is expressed in highly aggressive melanoma and breast cancer cell lines. Remarkably, inactivation of VE-cadherin triggered a significant loss of malignant traits (p...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352113/ https://ncbi.nlm.nih.gov/pubmed/27966446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13832 |
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