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Restoration of Gene Function by Homologous Recombination: from PCR to Gene Expression in One Step

We have developed a simple method for single-step cloning of any PCR product into a plasmid. A novel selection principle has been applied, in which activation of a drug selection marker is achieved following homologous recombination. In this method a DNA fragment is amplified by PCR with standard ol...

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Bibliografische gegevens
Hoofdauteurs: Yosef, Ido, Bloushtain, Noga, Shapira, Michal, Qimron, Udi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC535207/
https://ncbi.nlm.nih.gov/pubmed/15574912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.12.7156-7160.2004
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