Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

Zoledronic acid (ZA) is a biphosphonate used for osteoporosis treatment and also proved to be effective to reduce the pain induced by bone metastases when used as adjuvant therapy in solid cancers. However, it has been recently proposed that ZA could have direct anti-tumour effects, although the mol...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Comito, Giuseppina, Segura, Coral Pons, Taddei, Maria Letizia, Lanciotti, Michele, Serni, Sergio, Morandi, Andrea, Chiarugi, Paola, Giannoni, Elisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352046/
https://ncbi.nlm.nih.gov/pubmed/27223431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9497
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