Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

Zoledronic acid (ZA) is a biphosphonate used for osteoporosis treatment and also proved to be effective to reduce the pain induced by bone metastases when used as adjuvant therapy in solid cancers. However, it has been recently proposed that ZA could have direct anti-tumour effects, although the mol...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Comito, Giuseppina, Segura, Coral Pons, Taddei, Maria Letizia, Lanciotti, Michele, Serni, Sergio, Morandi, Andrea, Chiarugi, Paola, Giannoni, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352046/
https://ncbi.nlm.nih.gov/pubmed/27223431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9497
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