Peptide modification results in the formation of a dimer with a 60-fold enhanced antimicrobial activity

Cationic antimicrobial peptides (CAMPs) occur naturally in numerous organisms and are considered as a class of antibiotics with promising potential against multi-resistant bacteria. Herein, we report a strategy that can lead to the discovery of novel small CAMPs with greatly enhanced antimicrobial a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thamri, Amal, Létourneau, Myriam, Djoboulian, Alex, Chatenet, David, Déziel, Eric, Castonguay, Annie, Perreault, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351969/
https://ncbi.nlm.nih.gov/pubmed/28296935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173783
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