Recurrent genetic defects on chromosome 5q in myeloid neoplasms

BACKGROUND: Deletion of chromosome 5q (del(5q)) is the most common karyotypic abnormality in myeloid neoplasms. MATERIALS AND METHODS: To define the pathogenic molecular features associated with del(5q), next–generation sequencing was applied to 133 patients with myeloid neoplasms (MDS; N = 69, MDS/...

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Pubblicato in:Oncotarget
Autori principali: Hosono, Naoko, Makishima, Hideki, Mahfouz, Reda, Przychodzen, Bartlomiej, Yoshida, Kenichi, Jerez, Andres, LaFramboise, Thomas, Polprasert, Chantana, Clemente, Michael J, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Sanada, Masashi, Cui, Edward, Verma, Amit K, McDevitt, Michael A, List, Alan F, Saunthararajah, Yogen, Sekeres, Mikkael A, Boultwood, Jacqueline, Ogawa, Seishi, Maciejewski, Jaroslaw P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351647/
https://ncbi.nlm.nih.gov/pubmed/28031539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14130
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