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Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts

Epidermal growth factor receptor mutant III (EGFRvIII) is exclusively expressed in tumors, such as glioblastoma, breast cancer and hepatocellular carcinoma, but never in normal organs. Increasing evidence suggests that EGFRvIII has clinical significance in glioblastoma prognosis due to its enhanced...

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發表在:Oncotarget
Main Authors: Liu, Xujie, Dong, Chengyan, Shi, Jiyun, Ma, Teng, Jin, Zhongxia, Jia, Bing, Liu, Zhaofei, Shen, Li, Wang, Fan
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351638/
https://ncbi.nlm.nih.gov/pubmed/28031526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14088
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