RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR

Small cell lung cancer (SCLC) is an aggressive cancer that represents ~15% of all lung cancers. Currently there are no targeted therapies to treat SCLC. Our genomic analysis of a metastatic SCLC cohort identified recurrent RICTOR amplification. Here, we examine the translational potential of this ob...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Sakre, Nneha, Wildey, Gary, Behtaj, Mohadese, Kresak, Adam, Yang, Michael, Fu, Pingfu, Dowlati, Afshin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351607/
https://ncbi.nlm.nih.gov/pubmed/27863413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13362
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